From the discovery of drugs and functional materials to the development of clean and sustainable energy technologies, numerous efforts have been devoted by academic and industrial communities. The promising developments toward addressing these challenges have been identified through innovative research on the control over the reactivity. The Wang Group explores useful novel synthetic reagents, catalytic paradigms, and molecular activation modes. For example, we are interested in new hypervalent iodine(III) reagents design, incorporation of fluorine and organofluorine groups, and cross coupling with boron-ate complexes based on transition metal catalysis, electrosynthesis, and photocatalysis. In addition, kinetic studies, isotope effects, spectroscopic methods, DFT calculations, characterization of intermediates, and other designed experiments are employed to gain an in-depth understanding of the mechanism. We hope that people will witness the widespread use of these reactions featuring high selectivity, efficiency, and practicality in organic synthesis.